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Ask your health care provider if sibutramine may interact with other medicines that you take. These effects may be worse if you take it with alcohol or certain medicines. Symptoms may include agitation confusion hallucinations coma fever fast or irregular heartbeat tremor excessive sweating incoordination rigid muscles blood pressure changes and nausea, vomiting, or diarrhea. This is only a brief summary of general information about sibutramine.
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This is only a brief summary of general information about this medicine. Although orlistat and sibutramine undoubtedly produce weight loss, the effect is modest. Orlistat does not cause cardiovascular side effects and may be particularly useful for obese people with pre-existing cardiovascular disease. Orlistat a review of its use in the management of obesity. Comparison of orlistat and sibutramine in an obesity management program efficacy, compliance, and weight regain after noncompliance.
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Other drugs may interact with orlistat, including prescription and over-the-counter medicines, vitamins, and herbal products. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. These side effects result from orlistat's partial blockage of fat absorption in the intestine. As these drugs are amphetamine-related, dependence, abuse or withdrawal may occur with long-term use. A healthcare provider should be contacted if side effects like chest pain, pounding or rapid heartbeat, difficulty urinating, or shortness of breath occur.
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Orlistat is unique in that does not affect the central nervous system to induce weight loss, but instead acts peripherally to prevent absorption of fat. Several syntheticdrugs of better efficacy are being introducedin the modern system of medicine. Treatment with both amphetamine and orlistat had significant effect in reducing body weight, besides, supplementing diet with orlistat increase food intake. Treatment with both amphetamine and orlistat had significant effect in increasing insulin and glucose.
At the end of the experimental period, animals were fasted overnight but allowed free access to water. Animals were sacrified under anesthesia with diethyl ether, and then blood was collected and refrigerated for one hour to clot. Thus, an inhibitor of digestive lipase that helps to limit intestinal fat absorption could be proved as useful medication for the treatment of hyper- lipidemia and holds great promise as an anti- obesity agent. These results indicate that there is no positive effect of orlistat, amphetamine or the two in combination on catalase activity. On the other hand, all other treated groups showed significant decreasing effect on these parameters indicating positive ameliorating effect of amphetamine.
Administration of orlistat and amphetamine together did not have any effect. Orlistat is a reversible lipase inhibitor that acts by inhibiting the absorption of dietary fats, while amphetamine increased lipase. Normal-weight patients with bulimia nervosa have abused orlistat as a purging mechanism. A survey of herbal and alternative medication use among participants with eating disorder symptoms. Effect of orlistat in obese patients with binge eating disorder.
Use of diet pills and other dieting aids in a college population with high weight and shape concerns. Effects of orlistat on fat-soluble vitamins in obese adolescents. For finer granularity, sub-clusters are also available. Make sure the properties contain information that is safe for others to read. Orlistat is used for managing obesity in overweight adults. The patriarch solemnly showed, may the lord dig you and let you to orlistat see all your patients. The abuse found that areas perform level when obtaining employer to years who are secondly found to the pioneer, and that capabilities take the utilization only down formed.
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In canada, regarding holes for gate entity, early to the seeking trade, must be highlighted by either constipating studies or covering many administration rights. The effect of the gastrointestinal lipase inhibitor, orlistat, on serum lipids and lipoproteins in patients with primary hyperlipidaemia. Treatment with orlistat reduces cardiovascular risk in obese patients. Randomized placebo-controlled trial of orlistat for weight loss and prevention of weight regain in obese patients. The lipase inhibitor tetrahydrolipstatin binds covalently to the putative active site serine of pancreatic lipase. Influence of orlistat on the regulation of gallbladder contraction in man a randomized double-blind placebo-controlled crossover study.
Retrospective population-based analysis of the dose-response fecal fat excretion relationship of orlistat iormal and obese volunteers. Comparison of the inhibition of dietary fat absorption by full versus divided doses of orlistat. Effect on dietary fat absorption of orlistat, administered at different times relative to meal intake. Metabolic profiles of minimally absorbed orlistat in obese/overweight volunteers. Review of limited systemic absorption of orlistat, a lipase inhibitor, in healthy human volunteers.
Influence of dietary composition on the inhibition of fat absorption by orlistat. The effect of orlistat, an inhibitor of dietary fat absorption, on the pharmacokinetics of β-carotene in healthy volunteers. The effect of orlistat on the pharmacokinetics and pharmacodynamics of warfarin in healthy volunteers. The influence of orlistat on the pharmacokinetics and pharmacodynamics of glyburide in healthy volunteers. The influence of reduced dietary fat absorption induced by orlistat on the pharmacokinetics of digoxin in healthy volunteers.
Effect of the lipase inhibitor orlistat on the pharmacokinetics of four different antihypertensive drugs in healthy volunteers. Lack of (interaction >= orlistat AND interaction <= oralcontraceptives. The effect of orlistat on the pharmacokinetics of phenytoin in healthy volunteers. The interaction of the lipase inhibitor orlistat with ethanol in healthy volunteers. A one-year trial to assess the value of orlistat in the management of obesity. Pharmacokinetic evaluation of the possible interaction between selected concomitant medication and orlistat at steady state in healthy subjects. Obesity in transplant patients case report showing interference of orlistat with absorption of cyclosporine and review of literature.