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Si bien su principio activo, el orlistat, logra la pérdida de peso, aparentemente también afectaría a los riñones, provocando daño renal. The benefits and coverage outlined here may change. Ask your health care provider if sibutramine may interact with other medicines that you take. These effects may be worse if you take it with alcohol or certain medicines. Symptoms may include agitation confusion hallucinations coma fever fast or irregular heartbeat tremor excessive sweating incoordination rigid muscles blood pressure changes and nausea, vomiting, or diarrhea. This is only a brief summary of general information about sibutramine.
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This is only a brief summary of general information about this medicine. Although orlistat and sibutramine undoubtedly produce weight loss, the effect is modest. Orlistat does not cause cardiovascular side effects and may be particularly useful for obese people with pre-existing cardiovascular disease. Orlistat a review of its use in the management of obesity. Comparison of orlistat and sibutramine in an obesity management program efficacy, compliance, and weight regain after noncompliance. Other drugs may interact with orlistat, including prescription and over-the-counter medicines, vitamins, and herbal products.
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The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Orlistat works by blocking the enzyme that breaks down fats in your diet. These side effects may get worse if you eat more fat than you should. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Properly discard this product when it is expired or no longer needed. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Hepatotoxicity the adverse effects of drugs and other chemicals on the liver.
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Review of limited systemic absorption of orlistat, a lipase inhibitor, in healthy human volunteers. Randomised placebo-controlled trial of orlistat for weight loss and prevention of weight regain in obese patients. Long-term systemic exposure of orlistat, a lipase inhibitor, and its metabolites in obese patients. One-year treatment of obesity a randomized, double-blind, placebo-controlled, multicentre study of orlistat, a gastrointestinal lipase inhibitor. The effects of sibutramine and orlistat on the ultrasonographic findings, insulin resistance and liver enzyme levels in obese patients with non-alcoholic steatohepatitis. Orlistat-associated adverse effects and drug interactions a critical review. Evaluation of efficacy and safety of orlistat in obese patients.
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Treatment with both amphetamine and orlistat had significant effect in increasing insulin and glucose. At the end of the experimental period, animals were fasted overnight but allowed free access to water. Animals were sacrified under anesthesia with diethyl ether, and then blood was collected and refrigerated for one hour to clot. Thus, an inhibitor of digestive lipase that helps to limit intestinal fat absorption could be proved as useful medication for the treatment of hyper- lipidemia and holds great promise as an anti- obesity agent.
These results indicate that there is no positive effect of orlistat, amphetamine or the two in combination on catalase activity. On the other hand, all other treated groups showed significant decreasing effect on these parameters indicating positive ameliorating effect of amphetamine. Administration of orlistat and amphetamine together did not have any effect. Orlistat is a reversible lipase inhibitor that acts by inhibiting the absorption of dietary fats, while amphetamine increased lipase. Normal-weight patients with bulimia nervosa have abused orlistat as a purging mechanism.
These side effects result from orlistat's partial blockage of fat absorption in the intestine. A survey of herbal and alternative medication use among participants with eating disorder symptoms. Effect of orlistat in obese patients with binge eating disorder. Use of diet pills and other dieting aids in a college population with high weight and shape concerns.
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