Orlistat side effects – Precautions and Warnings With Orlistat
Orlistat works by blocking the enzyme that breaks down fats in your diet. These side effects may get worse if you eat more fat than you should. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of particular drug is safe, appropriate or effective for you or anyone else.
Orlistat Uses, Dosage amp Side Effects Drugs com
They are the natural effects of orlistat's fat-blocking action and are actually signs that the medication is working properly. Call your doctor for medical advice about side effects. Stop taking orlistat and tell your doctor right away if you become pregnant. The absence of a warning for a given drug or drug combination io way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects.
Orlistat Oral Uses, Side Effects, Interactions, Pictures, Warnings amp Dosing WebMD
Due to its negligible absorption orlistat does not have negative impact on cardiovascular system or other body systems. Orlistat is as beneficial as metformin in the treatment of polycystic ovarian syndrome. The effects of anti-obesity intervention with orlistat on microvascular endothelial function. Influence of orlistat on bone turnover and body composition. Long-term effects of weight-reducing drugs in hypertensive patients. Orlistat improves endothelial function in obese adolescents a randomised trial.
The effects of orlistat in patients with diabetes improvement in glycaemic control and weight loss. The present study refers to orlistat, sibutramine, and rimonabant. Simultaneous use of orlistat and sibutramine occurred in six cases. Since weight loss offers no potential benefit to a pregnant woman and may result in fetal harm, orlistat is contraindicated during pregnancy. Orlistat is taken at mealtimes to prevent fat that is eaten in the meals from being broken down and absorbed by the body. Instead, the fat passes though the gut and is excreted in the faeces. Orlistat should be used alongside increased exercise and a reduced calorie, lower fat diet.
If you take orlistat with a meal that is very high in fat you are more likely to experience digestive side effects such as wind, oily spotting from the rectum, sudden bowel motions, and soft, fatty or oily stools. The safety of orlistat during pregnancy has not been established. The following are some of the side effects that are known to be associated with orlistat. You are less likely to experience digestive side effects if you follow the instructions on what to eat while taking orlistat and do not take it with meals that are high in fat. Talk to your doctor, nurse or pharmacist if you want any more information about the possible side effects of orlistat. Similarly, check with your doctor or pharmacist before taking any new medicines while taking orlistat, to make sure that the combination is safe.
Orlistat may also reduce the absorption of certain medicines from the gut, for example those listed below, and so could make these less effective. You should tell your doctor if you think your medicine has become less effective after starting orlistat. If you are taking medicines for diabetes, you may need an adjustment in your dose if you lose weight while taking orlistat. Orlistat is not recommended for use in combination with acarbose for diabetes. Orlistat can cause diarrhoea, which if severe, can reduce the absorption of oral contraceptive pills from the gut and thus make them less effective at preventing pregnancy. If you are taking orlistat with one of these medicines your doctor may need to do some extra monitoring to make sure your medicine is still effective. It is unclear whether these cases were actually caused by orlistat or other factors.
In order to avoid these side effects, you should not eat too much fat while taking the drug. If you have these conditions or have had them in the past, talk with your healthcare provider before taking orlistat. Other drugs may interact with orlistat, including prescription and over-the-counter medicines, vitamins, and herbal products. Taking orlistat can make it harder for your body to absorb certain vitamins. Si bien su principio activo, el orlistat, logra la pérdida de peso, aparentemente también afectaría a los riñones, provocando daño renal. These effects may be worse if you take it with alcohol or certain medicines. These tests may be used to monitor your condition or check for side effects.
If you have questions about side effects, contact your health care provider. A reduced therapeutic effect of amiodarone is possible. No embryotoxicity or teratogenicity was seen in animals that received orlistat at doses much higher than the recommended human dose. In both adolescent studies, adverse effects were generally similar to those described in adults and included fatty/oily stool, oily spotting, and oily evacuation. The effect is the percentage of ingested fat excreted, referred to as fecal fat excretion percentage. The disposition of orlistat appeared to be similar betweeormal weight and obese subjects.
Although orlistat and sibutramine undoubtedly produce weight loss, the effect is modest. And with sibutramine side effetcs are headache, dry mouth and anorexia. Orlistat does not cause cardiovascular side effects and may be particularly useful for obese people with pre-existing cardiovascular disease. Orlistat a review of its use in the management of obesity.
Comparison of orlistat and sibutramine in an obesity management program efficacy, compliance, and weight regain after noncompliance. Hepatotoxicity the adverse effects of drugs and other chemicals on the liver. Review of limited systemic absorption of orlistat, a lipase inhibitor, in healthy human volunteers. Randomised placebo-controlled trial of orlistat for weight loss and prevention of weight regain in obese patients. Long-term systemic exposure of orlistat, a lipase inhibitor, and its metabolites in obese patients. One-year treatment of obesity a randomized, double-blind, placebo-controlled, multicentre study of orlistat, a gastrointestinal lipase inhibitor. The effects of sibutramine and orlistat on the ultrasonographic findings, insulin resistance and liver enzyme levels in obese patients with non-alcoholic steatohepatitis.